Researchers developed a way to directly reprogram human glial cells into PV interneurons without passing through a stem‑cell stage.
Researchers at Lund University in Sweden have created a method that makes it possible to transform the brain's support cells ...
Jonas Salk quietly built the polio vaccine through rigorous, methodical work in Pittsburgh: treating patients, refinin ...
Bone metastasis represents a complex complication of advanced human malignancies. Metabolic reprogramming plays a critical role in bone metastasis. Tumor cells hijack and alter local metabolic ...
Boston-based Life Biosciences is testing whether reprogramming human cells can slow or even reverse the effects of aging. Unsplash Life Biosciences, a Boston-based biotechnology company founded in ...
The POU4F3-tdTomato hair cell reporter becomes visible after ∼3 days of reprogramming. Representative images were acquired at 0-, 3- or 7-days post-doxycycline treatment. Scale bar represents 200 µm.
Not revised: This Reviewed Preprint includes the authors’ original preprint (without revision), an eLife assessment, and public reviews. In this manuscript, Rainey et al investigated the effects of ...