pharmaphorum

Strategies for success with comparator clinical trials

Craig Morgan outlines why comparator clinical trials are useful and provides points to consider to ensure the best outcome. In clinical trials, a comparator drug (defined as ‘an investigational or ...
pharmaphorum

How to Successfully Employ External Comparator Arm Studies Using Real World Data

Despite randomised clinical trials (RCTs) being the gold standard for drug approval studies, the shift towards precision medicine has increased the use of single-arm trials (SATs). SATs lack results ...
IEEE

Predictive comparators with adaptive control

Abstract: We describe an architecture that adds a linear predictor and adaptive control to a comparator to greatly reduce its delay. The linear predictor feeds an estimated future signal to the ...
IEEE

A 1.2-V Dynamic Bias Latch-Type Comparator in 65-nm CMOS With 0.4-mV Input Noise

Abstract: A latch-type comparator with a dynamic bias pre-amplifier is implemented in a 65-nm CMOS process. The dynamic bias with a tail capacitor is simple to implement and ensures that the ...
qualitysafety.bmj

The Global Comparators project: international comparison of 30-day in-hospital mortality by day of the week

Correspondence to Dr Milagros Ruiz, Dr Foster Unit, PCPH Imperial College London, 3 Dorset Rise, London EC4Y 8EN, UK; m.ruiz{at}imperial.ac.uk Objective To examine the association of mortality by day ...