In a recent study published in Cell, researchers examined the wealth of information available regarding the heterogeneity of tissue macrophages. They pursued a conceptual framework for better ...

Even its name is a testament to how enigmatic the tingible macrophage has been. Tingible, which means stainable, certainly gives no clues to its functions – but was, at least, one thing that was known ...

Macrophages are the specialized phagocytic cells that respond to toxic particle depositions to exert inflammatory and clearance responses. These long-lived immune cells engulf foreign substances like ...

Scientists have uncovered a powerful genetic switch that helps some of the body’s most important immune cells grow up properly and keep our organs healthy. The switch, called MafB, guides immature ...

The immune system is made up of various cells that combat disease. Each cell plays a pivotal role in mediating infection to ...

Systemic lupus erythematosus (SLE) involves ongoing inflammation, tissue damage from immune complexes, and incomplete immune resolution. A key factor ...

Tumor-associated macrophages (TAMs) within the tumor microenvironment (TME) exhibit significant metabolic dysregulation, ...

Macrophages and other immune cells are the natural frontline immune warriors of our body, defending the body against invading pathogens and cancer cells. Yet despite their innate "combat" capabilities ...

The research was led by Prof. Fuping Zhang from the Institute of Microbiology, Chinese Academy of Sciences, in collaboration with Prof. Jian Song from the Guangxi Zhuang Autonomous Region People's ...

The understanding of how macrophages regulate their response to toxic particles via two independent pathways could uncover therapeutic opportunities to quell inflammation BIRMINGHAM, Ala. – Human ...