Researchers show that loss of the SPRTN enzyme lets DNA–protein crosslinks accumulate, leak DNA into the cytoplasm, activate ...

DNA is often described as the instruction manual for building the fundamental components of life. Proteins are helpers that ...

Although DNA is tightly packed and protected within the cell nucleus, it is constantly threatened by damage from normal ...

By Tarun Sai Lomte Blood-based DNA repair and stress-response signals reveal a brief molecular window preceding Parkinson’s ...

Particle therapy, including proton and carbon ion radiotherapy, represents a major advancement in cancer treatment due to its ...

DNA can sustain serious injuries called double strand breaks, in which both strands of the helix snap. These breaks are among the most dangerous forms of DNA damage and immediately trigger the cell's ...

A new study shows that cancer damages its own DNA by pushing key genes to work too hard. Researchers found that the most ...

A team of researchers have identified a fundamental mechanism that links the 24-hour circadian cycle to the precise repair of DNA breaks. This study, conducted by researchers from the Andalusian ...

Objectives Understanding the molecular changes in the preclinical synovium is crucial for identifying factors that drive ...

If severe DNA damage is not repaired, the consequences for the health of cells and tissues are dramatic. A study led by ...