A novel iPSC-derived lung-on-chip model mimics human alveolar tissue, revealing macrophage-driven tuberculosis responses.

The goal of the study is to investigate host genetic and immunologic predictors of resistance to M. tuberculosis infection and progression from latent M. tuberculosis infection to active tuberculosis ...

The chip can simulate breathing and lung disease for an individual, holding promise for testing personalized treatments for tuberculosis.

CHAPEL HILL -- New research led by a University of North Carolina at Chapel Hill scientist shows for the first time how Mycobacterium tuberculosis, the germ responsible for TB, uses a system for ...

New observations of the early stages of tuberculosis infection may turn scientists' understanding of the bug's pathogenesis on its head: clumps of immune cells, called granulomas, long thought to ...

Down-regulation of plasma exosome-derived apolipoproteins APOA1, APOB, and APOC1 indicates DR-TB status and lipid metabolism regulation in pathogenesis. Group case-controlled study assessed 17 drug ...

The ability of Mycobacterium tuberculosis (MTB), a serious respiratory infection, to form snake-like cords was first noted nearly 80 years ago. In a study published October 20 in the journal Cell, ...

This is a preview. Log in through your library . Abstract Background. Tuberculosis is an urgent public health problem caused by Mycobacterium tuberculosis infection. Many factors, including host ...

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Tuberculosis and polio vaccines are being tested to see if they could possibly protect patients from COVID-19, scientists told The Washington Post. “This is the only vaccine in the world that can be ...