Getting DNA into a living cell sounds simple, until you remember the cell’s outer membrane acts like a guarded wall. DNA strands carry a negative charge, and they do not cross that wall easily.

Researchers from Tokyo Metropolitan University have created a new molecule which carries DNA into biological cells, to treat or vaccinate against illnesses. Many existing options rely on molecules ...

A team led by Professor Shoichiro Asayama at Tokyo Metropolitan University has synthesized a charge-free molecule designed to sneak plasmid DNA into living cells via hydrogen bonding, dramatically ...

New workflow validated on Dynamic Devices Lynx® delivers scalable plasmid DNA extraction from Midi to Maxi-prep volumes ...

Success in gene and cell therapy is driving demand for plasmid DNA which is a key reagent to produce viral vectors, both for commercial products as well as the breadth of different vectors for the ...

The use of in vivo electroporation (EP) as a therapeutic gene delivery approach has been successfully used in a variety of applications including cancer therapy and the regulation of protein levels to ...

Hopewell-based team delivers on ProBio's promise of speed, quality, and reliability—offering a transparent, fixed-cost model and ≥85% supercoiled plasmid DNA in record time for clinical programs. The ...

Increase in funding for R&D activities, surge in awareness regarding gene therapy, and rise in prevalence of cancer, viral infections, and genetic disorders drive the growth of the global viral ...

Bacterial plasmids are circular or linear double-stranded DNA molecules defined by their capability of autonomous replication in the hosts. They are critical sources for microbial evolution and genome ...

Are plasmid DNA issues impacting your mRNA program delivery? Many biotech and pharma companies focused on advanced therapy manufacturing are experiencing challenges associated with their pDNA supply, ...