The New England Journal of Medicine

Triplet Therapy, Transplantation, and Maintenance until Progression in Myeloma

In patients with newly diagnosed multiple myeloma, the effect of adding autologous stem-cell transplantation (ASCT) to triplet therapy (lenalidomide, bortezomib, and dexamethasone [RVD]), followed by ...
News Medical

DNA Damage Repair and the Progression of the Cell Cycle

During S-phase, DNA replication takes place in five stages. They are: initiation, unwinding, primer synthesis, elongation, and termination. Helicase enzymes “unwind” the DNA double helix, and ...
ascopubs.org

Ability of cell-cycle progression score to predict risk for progression to metastatic disease and disease-specific mortality in prostate cancer patients after prostatectomy.

Bone metabolism biomarkers (BMB) and progression-free survival (PFS) in men with metastatic hormone-sensitive prostate cancer (HSPC): SWOG S1216, a phase III trial of androgen deprivation therapy (ADT ...
ascopubs.org

Cell cycle progression score to predict metastatic progression of clear cell renal cell carcinoma after resection.

Phase II trial of neoadjuvant axitinib in patients with locally advanced nonmetastatic clear cell renal cell carcinoma. Dovitinib in first-line renal cell carcinoma: An investigation into tumour gene ...